One of only four Oklahoma City defeats this season was against the Spurs in San Antonio, but there was no repeat on home territory as Ibaka, who also pulled down 17 rebounds, was backed by 22 points from Russell Westbrook and 20 from Kevin Martin.
Tony Parker and Gregg Popovich led the Spurs, against the team who beat them in last season's Western Conference finals, with 14 points each.
The New York Knicks lost their 100 per cent home record this season as Jeremy Lin and the Houston Rockets claimed a 109-96 victory.
Lin scored 22 points against his old team, while James Harden led the Houston attack with 28 points and 10 rebounds, consigning the Knicks to their first defeat in 11 home games.
New York's Chris Copeland led all scorers with 29 points.
Jamal Crawford and Blake Griffin had 15 points apiece to lead five Los Angeles Clippers players in double figures as they extended their winning streak to 10 games with an 88-76 victory over the Detroit Pistons.
Shannon Brown scored 22 points to help the Phoenix Suns rally from 19 points down to beat the Sacramento Kings 101-90.
Glen David poured in 28 points in the Orlando Magic's 102-93 win over the Minnesota Timberwolves, while the Memphis Grizzlies overcame the Chicago Bulls 80-71.